Hyperactive signaling pathways of some aggressive blood cancer cells can be tamped down by a previously unrecognized protein complex, ensuring the cancer's survival. If one component of the complex is ...
New research shows that physical pressure from brain tumors or injuries triggers a "self-destruction" program in neurons, leading to irreversible brain damage.
The landscape of peptide-based research continues to broaden as investigators pursue compounds capable of interacting with molecular networks involved in cellular communication, structural maintenance ...
Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...
A team of researchers at RPI, in collaboration with the University of South Florida, University of North Carolina, and The Neural Stem Cell Institute, have made a discovery that opens the door to new ...
A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...
New research from the University of St Andrews has discovered a crucial piece in the puzzle of how all animals with a spine—including all mammals, fish, reptiles and amphibians—evolved. In a paper ...
Scientists have uncovered an unexpected genetic shift that may explain how animals with backbones first emerged and became so diverse.
A genetics‑guided drug, compound 6, targets CARD9 to subtly calm gut inflammation in Crohn’s disease, pointing to safer, longer‑lasting, precision treatments.
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