Immune checkpoint inhibitor therapy (ICI)-induced myositis (irMyositis) occurs in about 1% of patients treated with anti-PD1 or anti-CTLA-4 antibodies and can be debilitating or even fatal. We ...
The publication of the draft human genome in 2001 introduced a post-genomic era that promised global resolution of the molecular landscape in both preclinical and clinical research environments 1. To ...
Using genomic and transcriptional data has greatly improved the understanding of multiple aspects of human physiology. A new paper in PNAS reports on molecular-level associations of co-occurring ...
Levels of immune responses in tertiary lymphoid structures of non-small cell lung cancer (NSCLC) and association with survival. Predication of clinical outcomes of advanced cutaneous squamous cell ...
Inflammation and mitochondrial function as mechanisms in accelerated aging (AA) across substance use disorders (SUDs). This figure presents a proposed model linking genes associated with ...
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