A new paper published in Nature Biotechnology this week titled, “Template-independent enzymatic synthesis of RNA oligonucleotides,” provides details of a method for synthesizing single-stranded RNA ...

What the research is about Inside our cells, DNA-the blueprint of life-and RNA, which supports cellular functions based ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

The findings, published in Nature Metabolism, open a new path toward future treatments for severe mitochondrial diseases that currently have no cure Nucleotide synthesis—the production of the basic ...

Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division. In most animal cells, this process depends closely on properly functioning ...

There’s been this dream for decades. What if we could just print out an entire gene directly, one base at a time? —Daniel Lin-Arlow, Ansa Biotechnologies As scientists set their sights on cell and ...

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...

Purine nucleotides are essential for cell growth and function as they serve as nucleic acid building blocks, signaling molecules, and energy carriers. Treatments that inhibit their synthesis offer a ...