Sickle cell anemia (HbSS) is the homozygous dominant variant and the most common and severe form of the disease. Whereas patients who only inherited one gene encoding for abnormal HbS and a different ...

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report. The ...

Sickle cell disease is inherited at birth when you receive related genes from both parents. One gene usually causes sickle cell trait (SCT), which often has no health problems. The main sickle cell ...

If you or someone you know has sickle cell disease (SCD), you may have heard of Lyfgenia, one of two gene therapies approved for this condition. Gene therapies are the only treatments for SCD that can ...

Sickle cell disease is a hereditary condition, which means a person inherits it from their biological parents. The condition occurs when a person inherits two copies of the hemoglobin beta (HBB) gene ...

Sickle cell disease is a group of inherited blood disorders. It causes red blood cells to take on a crescent (sickle) shape and become rigid. These cells can break apart easily, leading to anemia.