Proteins targeting actin filament barbed ends play a pivotal role in motile processes. While formins enhance filament assembly, capping protein (CP) blocks polymerization. On their own, they both bind ...

The actin cytoskeleton is critical for many cellular processes, including migration, polarization, cytokinesis and adhesion. Actin filaments are polar structures, possessing a fast-growing 'barbed' ...

Actin is a highly abundant protein that controls the shape and movement of all our cells. Actin achieves this by assembling into filaments, one actin molecule at a time. The proteins of the formin ...

Metformin (Formin (500 mg)) is an oral antidiabetic agent, prescribed for type 2 diabetes. It helps control blood sugar levels. The information provided on this page is intended to serve as a ...

Actin is a highly abundant protein that controls the shape and movement of all our cells. Actin achieves this by assembling into filaments, one actin molecule at a time. There are as many as 15 ...

Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing ...

Metformin (Formin) is an oral antidiabetic agent, prescribed for type 2 diabetes. It helps control blood sugar levels. The information provided on this page is intended to serve as a comprehensive ...

Formins are made of two identical parts (red, orange) that encircle the actin (grey) filament in a ring-like conformation. “Our discovery allows us to interpret decades of biochemical studies on ...