Post-translational modification by ubiquitin and ubiquitin-like proteins (ubls) regulates almost all aspects of cellular function. Although it is known that E1, E2 and E3 enzymes work together in a ...
At the start of each ubiquitin-like protein (UBL) cascade is an E1 enzyme, which activates the UBL and then directs the UBL to downstream pathways. UBL proteins and E1 (or activating) enzymes have ...
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